Stephanie Stuteley
2024: Dr Stephanie Stuteley (Ngāti Tarāwhai, Ngāti Pikiao) of Waipapa Taumata Rau The University of Auckland will research a promising new method for treatment of tuberculosis (TB)
Antimicrobial resistance is an urgent global health threat, particularly for TB, which causes nearly one third of deaths from drug-resistant infections. TB bacteria produce proteins containing iron-sulfur clusters which it uses to counteract both the host's immune system and a major class of anti-TB drugs. Dr Stuteley has already established the only facility in Aotearoa New Zealand equipped to produce and study these iron-sulfur proteins, which requires oxygen-free conditions. Dr Stuteley will study the biochemical pathways which produce these iron-sulfur clusters in TB bacteria and how these protective pathways can be disrupted. This project will generate essential new knowledge for the development of new TB treatments.